Migraine remains one of the most disabling neurological disorders worldwide, yet with so many treatment options, NSAIDs, triptans, and newer agents like the gepants, GPs face uncertainty about which to recommend first.

A BMJ systematic review and network meta-analysis, involving nearly 90,000 participants, provides a comprehensive comparison to date of 17 drugs.

In this interview we speak to the authors and discuss how the treatments ranked for pain outcomes and tolerability, and how these findings can guide evidence-based decision-making in primary care.

Endometriosis affects one in nine Australian women, yet diagnosis is often delayed by many years due to the wide variation in symptoms and the tendency for both patients and clinicians to normalise menstrual pain.

In this interview, we speak with a patient about her experience of persistent pelvic pain, diagnostic delay and the ongoing need for treatment beyond surgery. We then discuss practical, evidence-based steps for primary care – how to recognise when endometriosis should be suspected, simple first-line management options, the role of PBS-listed hormonal therapies, and when further investigation or referral is appropriate.

This conversation provides clear guidance to help GPs initiate supportive, structured management programmes for women with suspected or confirmed endometriosis.

Tackling Hypertension Head-On Miniseries (Part 7)

Ready to confidently tackle hypertension in your everyday practice? In this episode of our hypertension miniseries, Dr Sneha Wadhwani and Dr Om Narayan use practical case studies to show how to reach BP targets in primary care. Learn when to step up treatment, how to use single-pill combinations effectively, and tips for using home and ambulatory monitoring to guide decisions.

Get clear, practical strategies to overcome therapeutic inertia and protect your patients from the risks of uncontrolled hypertension.

This audio file contains all 4 interviews in this edition.

• Track 1: Everything Menopause Miniseries (Part 9): PBS, MHT, & The Menopause Moment: What GPs Need to Know
• Track 2: When Heavy Periods Aren’t ‘Just Part of Life’. Understanding Heavy Menstrual Bleeding
• Track 3: Obstructive Sleep Apnoea; A Silent Health Crisis Miniseries (Part 2): Beyond CPAP: Changing How We Manage OSA
• Track 4: Dietary Challenges in T2D Miniseries (Part 5): Weight Loss at What Cost? Managing Muscle & Nutrition on GLP-1s

To view reference lists or product information please go to the individual interviews.

Dietary Challenges in T2D Miniseries (Part 5)

GLP-1 receptor agonists have transformed type 2 diabetes management, delivering substantial weight loss and cardiovascular benefits.

But with growing use comes an emerging concern: accelerated muscle loss and nutritional deficiencies in some patients.

In this expert discussion we explore the evidence, outline at-risk groups, and share practical strategies, including the role of DSNFs, to help GPs protect muscle health, optimise nutrition, and maintain patient function while on GLP-1 therapy.

Obstructive Sleep Apnoea: A Silent Health Crisis (Part 2)

Obstructive sleep apnoea (OSA) remains significantly underdiagnosed, despite its strong links to obesity, cardiovascular disease, and metabolic complications. Until now, management has largely relied on mechanical interventions such as CPAP, with variable patient adherence.

In this interview we discuss the role of a pharmacological treatment, recently approved in Australia for the treatment of moderate to severe OSA in adults with obesity.

Learn how these developments could change the way GPs approach OSA management, whether alongside CPAP or as an alternative pathway.

Heavy menstrual bleeding affects around one in four women, yet symptoms are often normalised by both patients and clinicians—delaying diagnosis and treatment.

This discussion covers how to recognise the condition early, ask targeted screening questions, and use effective first-line treatments.

We also explore when to refer, fertility-sparing options, and practical ways GPs can proactively screen during routine consults to improve outcomes.

Menopausal hormone therapy (MHT) can be transformative for many women, yet fewer than 40% continue treatment beyond the first year. With new PBS listings for body-identical options, affordability and access are improving, but optimal prescribing still relies on careful initiation, monitoring, and adjustment. In this interview we explore:

• # Key PBS updates for MHT, including cost and 60-day dispensing
• # When and how to initiate therapy, and tailoring the right regimen
• # Getting progesterone scheduling right to protect the endometrium
• # Managing the common challenges of the first three months
• # Supporting women with evidence-based, individualised care

Practical, GP-focused advice to help you navigate prescribing confidently, while ensuring your patients feel heard and supported.

This audio file contains all 5 interviews in this edition.

• Track 1: Let’s Talk Muscle Health Miniseries (Part 4): Poor Muscle Health and Chronic Disease – Don’t Wait for the Fall.
• Track 2: Let’s Talk Muscle Health Miniseries (Part 5): Are You Testing for Muscle Health? Why Every GP Should Be.
• Track 3: Obstructive Sleep Apnoea; A Silent Health Crisis Miniseries (Part 1): Could you be Missing OSA in your day-to-day Patients?
• Track 4: The Baker Lipid Miniseries (Part 4): Adherence Matters: Strategies for Improving the Lifelong Management of High Cholesterol
• Track 5: COVID-19 & CVD: Managing High-Risk Patients

To view reference lists or product information please go to the individual interviews.

Over 80% of Australian GPs believe they should screen for sarcopenia, yet few currently do so -primarily due to limited access to tools or training.

In this episode, we discuss the Muscle Health Algorithm, a GP-friendly resource designed to help detect and manage poor muscle health before it leads to sarcopenia.

Learn how to perform the handgrip strength and five-times sit-to-stand tests, identify at-risk patients over 50, and confidently start interventions that maintain independence and quality of life in older Australians.