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Migraine remains one of the most disabling neurological disorders worldwide, yet with so many treatment options, NSAIDs, triptans, and newer agents like the gepants, GPs face uncertainty about which to recommend first.
A BMJ systematic review and network meta-analysis, involving nearly 90,000 participants, provides a comprehensive comparison to date of 17 drugs.
In this interview we speak to the authors and discuss how the treatments ranked for pain outcomes and tolerability, and how these findings can guide evidence-based decision-making in primary care.
GP, TV host, Author, and Podcaster.
Psychiatrist and Researcher at Oxford University.
Danish Headache Centre in Copenhagen.
GP Edition 167.
Supported by: Produced in November 2025 by DrivetimeRadio with the support of Viatris.
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